Mechanism of Action: Competes for angiotensin II binding sites in vascular smooth muscle
Contraindications: Pregnancy, breast feeding, limited effectiveness in black patients
Pregnancy Category:
- (First Trimester) C - Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
- (Second and Third Trimester) D - There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Common Medications (Brand -- Generic)
- Edarbi - Azilsartan
- Tablets: 40mg, 80mg
- Atacand - Candesartan*
- Tablets: 4mg, 8mg, 16mg, 32mg
- Avapro - Irbesartan
- Tablets: 75mg, 150mg, 300mg
- Cozaar - Losartan
- Tablets: 25mg, 50mg, 100mg
- Benicar - Olmesartan
- Tablets: 5mg, 20mg, 40mg
- Micardis - Telmisartan
- Tablets: 20mg, 40mg, 80mg
- Diovan - Valsartan*
- Tablets: 40mg, 80mg, 160mg, 320mg
Common Side Effects
- Hypotension
- Dizziness
Rare, but Potentially Deadly Side Effects
- Angioedema
Combination Drugs Containing ARBs:
- Atacand HCT - Candesartan/ HCTZ (Diuretic)
- Avalide - Irbesartan/ HCTZ (Diuretic)
- Hyzaar - Losartan/ HCTZ (Diuretic)
- Azor - Olmesartan/ Amlodipine (Calcium Channel Blocker)
- Benicar HCT - Olmesartan/ HCTZ (Diuretic)
- Tribenzor - Olmesartan/ Amlodipine/ HCTZ (Calcium Channel Blocker/ Diuretic)
- Micardis HCT - Telmisartan/ HCTZ (Diuretic)
- Exforge - Valsartan/ Amlodipine (Calcium Channel Blocker)
- Exforge HCT - Valsartan/ Amlodipine/ HCTZ (Calcium Channel Blocker/ Diuretic)
- Diovan HCT - Valsartan/ HCTZ (Diuretic)
Miscellaneous
- Almost always end in -sartan
Sorry for being a little late. It's been one of those weeks at work. Next post hopefully on Sunday... along with an FDA update.
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