Drug Classes: Fenofibric Acid Derivatives

Used to treat: In conjuction with diet and exercise to lower LDL, total cholesterol, triglycerides, & apolipoprotein

Mechanism of Action: Inhibit triglyceride synthesis

Contraindications: Hepatic impairment (including biliary cirrhosis), gallbladder disease, severe renal impairment, may increase effects of warfarin and HMG-CoA Reductase Inhibitors


Pregnancy Category: C - Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Common Medications (Brand -- Generic)

• Various Brands (See Below) - Fenofibrate
• Tricor - Tablets: 48mg, 145mg
• Trilipix - Delayed Release Capsules: 45mg, 135mg
• Triglide - Tablets: 50mg, 160mg
• Lofibra - Micronized Tablets: 54mg, 160mg
• Lofibra - Micronized Capsules: 67mg, 134mg, 200mg
• Antara - Micronized Capsules: 43mg, 130mg
• Lipofen - Capsules: 50mg, 100mg
• Lopid - Gemfibrozil
• Tablets: 600mg

Common Side Effects

• fatigue
• weakness
• rashes
• abdominal/epigastric pain
• diarrhea

Rare, but Potentially Deadly Side Effects

• Rhabdomyolysis

Combination Drugs Containing: None
Miscellaneous:

• usually contain -fib- in drug name